File:Serpin mechanism (S to R).png

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DescriptionSerpin mechanism (S to R).png	English: The inhibitory mechanism of serpins involved a large conformation change.The serpin (white) first binds a protease (grey) with the reactive centre loop (blue). When cleaved by the protease, this loop rapidly inserts into the A-sheet (light blue), deforming and inhibiting the protease. (PDB: 1K9O, 1EZX)
Date	13 December 2015
Source	Own work
Author	Thomas Shafee

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	Date/Time	Dimensions	User	Comment
current	23:04, 19 March 2016	3,000 × 3,000 (2.83 MB)	Evolution and evolvability	Colour tweaks
	09:55, 22 December 2015	1,800 × 1,868 (1.13 MB)	Evolution and evolvability	Higher resolution and darker grey for protease
	00:36, 20 December 2015	1,083 × 1,125 (498 KB)	Evolution and evolvability	blue arrow (inkeeping with Serpin mechanism.png scheme)
	11:52, 13 December 2015	1,083 × 1,125 (496 KB)	Evolution and evolvability	A-sheet colour
	11:33, 13 December 2015	1,150 × 1,111 (462 KB)	Evolution and evolvability	Cross-wiki upload from en.wikipedia.org

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